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- Causal Inference and Machine Learning Endocrine & Cardiovascular Epidemiology
Inoue K*, Saliba D, Gotanda H, Moin T, Mangione CM, Klomhaus AM, Tsugawa Y. Glucagon-Like Peptide-1 Receptor Agonists and Incidence of Dementia Among Older Adults With Type 2 Diabetes : A Target Trial Emulation. Ann Intern Med. 2025. Online ahead of print.
- Endocrine & Cardiovascular Epidemiology
Inoue K, Liu M, Aggarwal R, Marinacci LX, Wadhera RK. Prevalence and Control of Diabetes Among US Adults, 2013 to 2023. JAMA. 2025. Online Ahead of Print.
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Inoue K, Liu M, Aggarwal R, Marinacci LX, Wadhera RK*. Depressive Symptoms Among US Adults. JAMA Intern Med. 2025. Online Ahead of Print.
- Precision Medicine and Public Health
Furukawa TA, Noma H, Tajika A, Toyomoto R, Sakata M, Luo Y, Horikoshi M, Akechi T, Kawakami N, Nakayama T, Kondo N, Fukuma S, Wason JMS, Kessler RC, Lutz W, Cuijpers P. Personalised & optimised therapy (POT) algorithm using five cognitive and behavioural skills for subthreshold depression. NPJ Digit Med. 2025 Aug 20;8(1):531.
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Furukawa TA, Tajika A, Toyomoto R, Sakata M, Luo Y, Horikoshi M, Akechi T, Kawakami N, Nakayama T, Kondo N, Fukuma S, Kessler RC, Christensen H, Whitton A, Nahum-Shani I, Lutz W, Cuijpers P, Wason JMS, Noma H. Cognitive behavioral therapy skills via a smartphone app for subthreshold depression among adults in the community: the RESiLIENT randomized controlled trial. Nat Med. 2025 Jun;31(6):1830-1839.
- Endocrine & Cardiovascular Epidemiology
Inoue K*, Kazi DS, Vaduganathan M, Wadhera RK. Prescription Patterns for GLP-1 Receptor Agonists and SGLT2 Inhibitors by Physicians’ Years in Practice. J Gen Intern Med. 2025. Online Ahead of Print.
- Causal Inference and Machine Learning Precision Medicine and Public Health
Nianogo RA, O'Neill S, Inoue K. Generalized framework for identifying meaningful heterogenous treatment effects in observational studies: A parametric data-adaptive G-computation approach. J Stat Methods Med Res. 2025. Online Ahead of Print.
- Causal Inference and Machine Learning Precision Medicine and Public Health
Komura T, Bargagli-Stoffi FJ, Shiba K, Inoue K*. Two-Step Pragmatic Subgroup Discovery for Heterogeneous Treatment Effects Analyses: Perspectives Toward Enhanced Interpretability. Eur J Epidemiol. 2025 Online Ahead of Print.
- Causal Inference and Machine Learning Endocrine & Cardiovascular Epidemiology
Komura T, Tsugawa Y, Yabe D, Kondo N, Inoue K*. Depression Risk Associated with Spouses’ Diabetes and Cardiovascular Events: A Nationwide Cohort Study. Am J Epidemiol. 2025 Online Ahead of Print.
- Causal Inference and Machine Learning Precision Medicine and Public Health
Athey S, Inoue K, Tsugawa Y. Targeted Treatment Assignment Using Data from Randomized Experiments with Noncompliance. AEA Papers and Proceedings. 2025, 115: 1–6.
- Causal Inference and Machine Learning Precision Medicine and Public Health Endocrine & Cardiovascular Epidemiology
Inoue K*, Athey S, Baicker K, Tsugawa Y. Heterogeneous effects of Medicaid coverage on cardiovascular risk factors: secondary analysis of randomized controlled trial. BMJ. 2024; 386: e079377.
- Endocrine & Cardiovascular Epidemiology
Yagi R, Mori Y, Goto S, Iwami T, Inoue K*. Routine Electrocardiogram Screening and Cardiovascular Disease Events in Adults. JAMA Internal Medicine. 2024; 184(9):1035-1044.
- Causal Inference and Machine Learning Endocrine & Cardiovascular Epidemiology
Mori Y, Komura T, Adomi M, Yagi R, Fukuma S, Kondo N, Yanagita M, Duru OK, Tuttle KR, Inoue K*. Sodium-Glucose Cotransporter 2 Inhibitors and Cardiovascular Events Among Patients with Type 2 Diabetes and Low-to-Normal Body Mass Index: A Nationwide Cohort Study with Target Trial Emulation. Cardiovascular Diabetology. 2024;23(1):372.
- Causal Inference and Machine Learning Precision Medicine and Public Health
Inoue K*, Adomi M, Efthimiou O, Komura T, Omae K, Onishi A, Tsutsumi Y, Fujii T, Kondo N, Furukawa AT. Machine Learning Approaches to Evaluate Heterogeneous Treatment Effects in Randomized Controlled Trials: A Scoping Review. J Clin Epidemiol. 2024; 176: e111538.
- Causal Inference and Machine Learning Endocrine & Cardiovascular Epidemiology
Komura T, Tsugawa Y, Mayeda ER, Glymour MM, Inoue K*. Association of Cardiovascular Events with Spouse’s Subsequent Dementia. JAMA Neurology. 2024: 81(10): 1098-1099.
- Causal Inference and Machine Learning Precision Medicine and Public Health
Naito T, Inoue K (co-first), Namba S, Sonehara K, Suzuki K, BioBank Japan, Yamamoto K, Baba R, Kodama T, Otagaki Y, Okada A, Itcho K, Kobuke K, Ohno H, Biobank Japan, Matsuda K, Kondo N, Toda T, Yamauchi T, Kadowaki T, Okada Y. A machine learning approach reveals heterogeneous association of environmental factors with diseases across polygenic risk scores: an application to cardiovascular diseases and type 2 diabetes. Communications Medicine. 2024; 4(1): 181.
- Causal Inference and Machine Learning
Inoue K*, Sakamaki K, Komukai S, Ito Y, Goto A, Shinozaki T. Confounder Selection and Sensitivity Analyses to Unmeasured Confounding from Epidemiological and Statistical Perspectives. Journal of Epidemiology. 2024; 35(1): 3-10.
- Causal Inference and Machine Learning Endocrine & Cardiovascular Epidemiology
Inoue K*, Naito T, Fujii R, Sonehara K, Yamamoto K, Baba R, Kodama T, Otagaki Y, Okada A, Itcho K, Kobuke K, Ohno H, BioBank Japan, Morisaki T, Hattori N, Goto A, Nishikawa T, Oki K, Okada Y. Primary aldosteronism and risk of cardiovascular outcomes: Genome-wide association and Mendelian randomization study. J. Am. Heart Assoc. 2024; 13(15): e034180.
- Endocrine & Cardiovascular Epidemiology
Sohn SY, Inoue K, Rhee CM, Leung AM. Risks of Iodine Excess. Endocrine Reviews. 2024; 45(7): 858-879.
- Causal Inference and Machine Learning Endocrine & Cardiovascular Epidemiology
Komura T, Tsugawa Y, Kondo N, Inoue K*. Depression Onset After a Spouse’s Cardiovascular Event: A Nationwide Analysis in Japan. JAMA Network Open. 2024;7(4): e244602.
- Causal Inference and Machine Learning Precision Medicine and Public Health
Shiba K, Inoue K*. Harnessing Causal Forests for Epidemiologic Research: Key Consideration. Am J Epidemiol. 2024:kwae003.
- Precision Medicine and Public Health Endocrine & Cardiovascular Epidemiology
Inoue K*, Athey S, Tsugawa Y. Machine-learning-based high-benefit approach versus conventional high-risk approach in blood pressure management. International Journal of Epidemiology. 2023;52(4):1243-1256
- Causal Inference and Machine Learning Endocrine & Cardiovascular Epidemiology
Inoue K*, Seeman T, Nianogo R, Okubo Y. The Effect of Poverty on the Relationship between Household Education Levels and Obesity in U.S. Children and Adolescents: An Observational Study. The Lancet Regional Health - Americas. 2023;25:100565.
- Endocrine & Cardiovascular Epidemiology
Inoue K, Guo R, Lee M, Neverova N, Ebrahimi R, Currier J, Bashir M, Leung AM. Iodine-Induced Hypothyroidism and Long-term Risks of Incident Heart Failure. Journal of American Heart Association. 2023;12(20):e030511.
- Endocrine & Cardiovascular Epidemiology
Inoue K, Guo R, Lee M, Ebrahimi R, Neverova N, Currier J, Bashir M, Leung AM. Iodine-Induced Hyperthyroidism and Long-term Risks of Incident Atrial Fibrillation and Flutter. J Clin Endocrinol Metab. 2023;108(10):e956-e962.
- Endocrine & Cardiovascular Epidemiology
Inoue K*, Tsugawa Y, Mayeda ER, Ritz B. Association of Daily Step Patterns with Mortality in US adults. JAMA Network Open. 2023;6(3):e235174.
- Causal Inference and Machine Learning
Goto R, Kawachi I, Kondo N, Inoue K. Contribution of Vaccinations to Reducing Socioeconomic Disparities in COVID-19 Deaths Across US counties. Annals of Epidemiology. 2023;86:65-71.e3.
- Endocrine & Cardiovascular Epidemiology
Naito T, Inoue K, Sonehara K, Baba R, Kodama T, Otagaki Y, Okada A, Itcho K, Kobuke K, Kishimoto S, Yamamoto K, BioBank Japan, Morisaki T, Higashi Y, Hinata N, Arihiro K, Hattori N, Okada Y, Oki K. Genetic risk of primary aldosteronism and its contribution to hypertension: a cross-ancestry meta-analysis of genome-wide association study. Circulation. 2023;147(14):1097-1109.
- Causal Inference and Machine Learning Endocrine & Cardiovascular Epidemiology
Sato K, Noguchi H, Inoue K, Kawachi I, Kondo N. Retirement and cardiovascular disease: A longitudinal study in 35 countries. Int J Epidemiology. 2023;52(4):1047-1059.
- Causal Inference and Machine Learning Precision Medicine and Public Health
Goto R, Inoue K, Osawa I, Baicker K, Fleming S, Tsugawa Y. Machine learning detects heterogeneous effects of Medicaid coverage on depression. American Journal of Epidemiology. 2023;kwae008.
- Causal Inference and Machine Learning Precision Medicine and Public Health Endocrine & Cardiovascular Epidemiology
Inoue K*, Seeman T, Horwich T, Budoff M, Watson KE. Heterogeneity in the Association Between the Presence of Coronary Artery Calcium and Cardiovascular Events: A Machine Learning Approach in the MESA Study. Circulation. 2022;147(2):132-141.
- Endocrine & Cardiovascular Epidemiology
Inoue K, Rong G, Lee ML, Ebrahimi R, Neverova N, Currier J, Bashir M, Leung AM. Iodinated Contrast Administration and Risks of Thyroid Dysfunction: A Retrospective Cohort Analysis of the U.S. Veterans Health Administration System. Thyroid. 2022;33(2):230-238.
- Endocrine & Cardiovascular Epidemiology
Mori Y, Duru OK, Tuttle K, Fukuma S, Taura D, Harada N, Inagaki N, Inoue K*. Sodium-Glucose Cotransporter 2 Inhibitors and New-onset Type 2 Diabetes in Adults with Prediabetes: systematic review and meta-analysis of randomized controlled trials. Journal of Clinical Endocrinology and Metabolism. 2022;108(1):221-231.
- Causal Inference and Machine Learning
Inoue K*, Figueroa F, Kondo N, Tsugawa Y. Changes in Industry Marketing Payments to Physicians during the COVID-19 pandemic: Quasi-experimental Difference-in-difference Study. BMJ Medicine. 2022;1(1):e000219.
- Causal Inference and Machine Learning
Inoue K*, Ritz B, Arah OA. Causal Effect of Chronic Pain on Mortality through Opioid prescriptions: An Application of the Front-Door Formula. Epidemiology. 2022;33(4):572-580.
- Endocrine & Cardiovascular Epidemiology
Inoue K*, Horwich T, Bhatnagar R, Bhatt K, Goldwater D, Seeman T, Watson KE. Urinary stress hormones, hypertension, and cardiovascular events: the Multi-Ethnic Study of Atherosclerosis. Hypertension. 2021;78(5):1640-1647.
- Causal Inference and Machine Learning
Inoue K*, Tsugawa Y, Mangione CM, Duru OK. Association Between Industry Payments and Prescriptions of Long-acting Insulin: An Observational Study with Propensity-Score Matching. PLOS Medicine. 2021;18(6): e1003645.
- Endocrine & Cardiovascular Epidemiology
Inoue K, Figueroa JF, DeJong CD, Tsugawa Y, Orav EJ, Shen C, Kazi DS. Association Between Industry Marketing Payments and Prescriptions for PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Inhibitors in the United States. Circulation: Cardiovascular Quality and Outcomes. 2021;14(5):e007521.
- Causal Inference and Machine Learning
Inoue K, Hsu W, Arah OA, Prosper A, Aberle D, Bui A. Generalizability and transportability of the results from randomized controlled trials: An example using the National Lung Screening Trial. Cancer Epidemiology, Biomarkers & Prevention. 2021;30(12):2227-2234.
- Causal Inference and Machine Learning Endocrine & Cardiovascular Epidemiology
Inoue K*, Nianogo R, Telesca D, Goto A, Khachadourian V, Tsugawa Y, Sugiyama T, Mayeda ER, Ritz B. Low HbA1c levels and all-cause or cardiovascular mortality among people without diabetes: the US National Health and Nutrition Examination Survey 1999-2015. International Journal of Epidemiology. 2020;50(4):1373-1383.
- Causal Inference and Machine Learning Endocrine & Cardiovascular Epidemiology
Inoue K, Mayeda ER, Paul K, Haan MN, Ritz B. Mediation of the Associations of Physical Activity With Cardiovascular Events and Mortality by Diabetes in Older Mexican Americans. American Journal of Epidemiology. 2020;189(10):1124-1133.
- Causal Inference and Machine Learning Endocrine & Cardiovascular Epidemiology
Inoue K*, Goldwater D, Allison M, Seeman T, Watson K. Serum Aldosterone Concentration, Coronary Artery Calcium, and Mortality: The Multi-Ethnic Study of Atherosclerosis. Hypertension. 2020;76(1):113-120. - Selected as a High-impact paper for Fall 2020 -
- Endocrine & Cardiovascular Epidemiology
Inoue K*, Ritz B, Ebrahimi R, Rhee C, Brent GA, Leung AM. Association of Subclinical Hypothyroidism and Cardiovascular Disease With Mortality. JAMA Network Open. 2020;3(2):e1920745.
- Causal Inference and Machine Learning
Inoue K, Yan Q, Arah OA, Paul K, Walker DI, Jones DP, Ritz B. Air pollution and adverse birth outcomes: Mediation analysis using metabolomic profiles. Current Environmental Health Reports. 2020;7(3):231-242
- Endocrine & Cardiovascular Epidemiology
Inoue K*, Ritz B, Andersen SL, Ramlau-Hansen CH, Høyer BB, Bech BH, Henriksen TB, Bonefeld-Jørgensen EC, Olsen J, Liew Z. Perfluoroalkyl Substances and maternal thyroid hormones in early pregnancy; findings in the Danish National Birth Cohort. Environmental Health Perspectives. 2019;127(11):117002.
- Endocrine & Cardiovascular Epidemiology
Inoue K, Yamazaki Y, Kitamoto T, Hirose R, Saito J, Omura M, Sasano H, Nishikawa T. Aldosterone Suppression by Dexamethasone in Patients with Aldosterone-producing Adenoma Harboring Somatic KCNJ5 Mutations. Journal of Clinical Endocrinology and Metabolism. 2018;103(9):3477-3485.
- Endocrine & Cardiovascular Epidemiology
Inoue K*, Leung AM, Sugiyama T, Tsujimoto T, Makita N, Nangaku M, Ritz B. Urinary Iodine Concentrations and Mortality Among U.S. Adults. Thyroid. 2018;28(7):913-920.
- Endocrine & Cardiovascular Epidemiology
Inoue K*, Tsujimoto T, Saito J, Sugiyama T. Association between serum thyrotropin levels and mortality among euthyroid adults in the United States. Thyroid. 2016;26(10):1457-1465.